DNA is unwound and unzipped., Hydrogen bonds between complementary bases are broken to form two template strands, Primers are attached to the 3’ end of the leading strand to allow replication to start, DNA polymerase adds DNA nucleotides, using complementary base pairing, onto the deoxyribose sugar 3’ end of the new DNA strand, Many primers are used on the lagging strand at various 5’ ends as the strand is exposed. The ‘leading strand’ is replicated continuously , The ‘lagging strand’ is replicated in fragments. DNA polymerase adds DNA nucleotides onto the deoxyribose sugar 3’ end in fragments, The fragments are joined together by ligase.

Higher 1.2 DNA Replication Stages

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