Enzymes are large ____ that acts as biological ____. They speed up the rate of ____ reactions in living organisms Enzymes have a 3D structure and they work via the ____ and key theory. They have an active ____which has a ____ shape. The shape of the ____ fits exactly into the active site. Enzymes have an ____ temperature and pH that they work best at. The optimum level varies between enzymes. Increasing the ____ increases the rate of an enzyme-controlled reaction until it gets so hot that some of the ____ holding the enzyme together break and the enzyme becomes ____, so the active site no longer fits the ____. ____ changes can also denature enzymes.

B3 Enzymes

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