1) 1. What is the main purpose of hemostasis? a) A. To destroy platelets b) B. To remove calcium from blood c) C. To prevent and stop bleeding while maintaining blood fluidity d) D. To increase blood pressure 2) 2. Thromboxane A2 (TXA2) released by platelets mainly causes: a) A. Platelet inhibition b) B. Fibrin degradation c) C. Vasoconstriction and platelet activation d) D. Vasodilation 3) 3. Platelet activation involves all of the following EXCEPT: a) A. Decreasing intracellular signaling b) B. Granule release c) C. Shape change d) D. Thromboxane A2 formation 4) 4. Von Willebrand Factor (vWF) is essential for: a) A. Calcium binding in coagulation b) B. Platelet adhesion to exposed collagen c) C. Platelet aggregation only d) D. Fibrin cross-linking 5) 5. Which granule in platelets contains ADP, ATP, serotonin, and calcium? a) A. Dense granules b) B. Peroxisomes c) C. Lysosomal granules d) D. Alpha granules 6) 6. The intrinsic pathway of coagulation is initiated by: a) A. Contact with negatively charged molecules like collagen b) B. Platelet aggregation c) C. Tissue Factor exposure d) D. Thrombin activation 7) 7. Which vitamin is essential for proper synthesis of Factors II, VII, IX, and X? a) A. Vitamin D b) B. Vitamin K c) C. Vitamin B12 d) D. Vitamin C 8) 8. Warfarin works by: a) A. Activating Factor XIII b) B. Blocking recycling of vitamin K c) C. Increasing platelet aggregation d) D. Enhancing calcium binding 9) 9. Which enzyme complex converts prothrombin into thrombin on the platelet surface? a) A. Tenase complex b) B. Platelet integrin complex c) C. Prothrombinase complex d) D. Factor XIIIa 10) 10. The extrinsic pathway is primarily triggered by: a) A. Calcium depletion b) B. Tissue factor (TF) from damaged endothelium c) C. Activated platelets d) D. ADP release

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